September 9, 2021

TTM Post-Cardiac Arrest

In this episode of Critical Matters, we will discuss the results of the recently published TTM2 clinical trial and the current state of evidence for Targeted Temperature Management in the post cardiac arrest patient.

Our guest is Dr. Niklas Nielsen. Dr. Nielsen is an associate professor at the Department of Clinical Sciences at Helsingborg, Lund University, and consultant in Anesthesiology and Intensive Care at Helsingborg Hospital. He was the principal investigator for the TTM1 and TTM 2 clinical trials.

Additional Resources:
The International Cardiac Arrest Registry (INTCAR):
Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest:
Targeted Temperature Management at 33C versus 36C after Cardiac Arrest:
Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm:
2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care:

Books Mentioned in this Episode:
Oxygen: The Molecule that Made the World by Nick Lane:
Anna Karenina by Leo Tolstoy: