May 14, 2020

COVID - 19: Interrupting The VILI Vortex

In this episode of Critical Matters, we continue our exploration and discussion on respiratory support and mechanical ventilation with COVID-19.

Our guest is Dr. John J. Marini, a thought leader in the field of critical care. Dr. Marini is Director of Academic Programs in Research and Education for the Department of Medicine of the Regions Hospital in St. Paul, Minnesota. In most of his research, he has positioned himself at the interface between basic physiology and clinical medicine to develop insights into advancing clinical practice. In this episode, he discusses evolving concepts related to ventilator-induced lung injury and how they apply to respiratory support in patients with COVID-19.

Additional Resources:
Management of COVID-19 Respiratory Distress:
Time Course of Evolving Ventilator-Induced Lung Injury:
Static and Dynamic Contributors to Ventilator-induced Lung Injury in Clinical Practice. Pressure, Energy, and Power:

Books Mentioned in this Episode:
Nunn's Applied Respiratory Physiology by Andrew B. Lumb:
The Discoverers by DJ Boorstin:
Why Not Say it Clearly: A Guide to Scientific Writing by LS King.: